Tretinoin (Retinoic Acid)
Tretinoin (Retinoic Acid)
**CAS Number**: 302-79-4
**Molecular Formula**: C₂₀H₂₈O₂
**Color and Form**: Tretinoin typically appears as a yellow to light orange crystalline powder.
Tretinoin, also known as all-trans retinoic acid, is a derivative of vitamin A widely used in dermatology and oncology. It regulates cell growth and differentiation, making it effective for treating acne, photoaging, and certain cancers.
**Properties**:
– Sensitive to light and air, requiring storage in opaque, airtight containers.
– Soluble in organic solvents like ethanol and DMSO.
**Applications**:
1. **Dermatology**: Used topically to treat acne, wrinkles, and hyperpigmentation.
2. **Oncology**: Employed in the treatment of acute promyelocytic leukemia (APL).
**Effects**:
– Promotes skin cell turnover, reducing acne and improving skin texture.
– Induces differentiation of cancer cells, aiding in leukemia treatment.
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